https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Genetic variation in the bitter receptors responsible for epicatechin detection are associated with BMI in an elderly cohort https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45030 TAS2R4 (rs2233998 and rs2234001) and TAS2R5 (rs2227264) were associated with body mass index (BMI). Genotyping (Taqman qPCR assays) was performed on DNA extracted from blood samples (n = 563) from an elderly cohort. Homozygosity for the minor allele of all polymorphisms was significantly associated with a lower BMI in males. The TAS2R4-rs2233998 CC genotype, the TAS2R4-rs2234001 CC genotype and the TAS2R5-rs2227264 TT genotype were associated with lower BMI (2.1, 2.1 and 2.2 units; p = 0.002, 0.003 and 0.001, respectively). Epicatechin intake was not associated with BMI and genotype was not associated with epicatechin intake. This suggests that the association between TAS2R genotype and elevated BMI risk occurs through altered extra-oral responses and not directly via altered epicatechin intake.]]> Wed 26 Oct 2022 10:43:50 AEDT ]]> Interactions between taste genetics, diet and the gastrointestinal microbiota; consequences for metabolism https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52623 Wed 13 Mar 2024 13:53:59 AEDT ]]> Bitter taste genetics-the relationship to tasting, liking, consumption and health https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19565 Wed 11 Apr 2018 10:55:18 AEST ]]>